| Player | Comp/Att | Ps-Yards | Ps-TDs | int |
| Garoppolo, Jimmy | 16/22 | 176 | 2 | 0 |
|
| Player | Comp/Att | Ps-Yards | Ps-TDs | int |
| Lawrence, Trevor | 16/25 | 158 | 0 | 0 |
|
| Player | Att | Yards | ave | TDs |
| Samuel, Deebo | 8 | 79 | 9.9 | 1 |
| Wilson Jr., Jeff | 19 | 50 | 2.6 | 0 |
| Sermon, Trey | 10 | 32 | 3.2 | 0 |
| Garoppolo, Jimmy | 2 | 6 | 3.0 | 0 |
| Lance, Trey | 3 | 4 | 1.3 | 0 |
|
| Player | Att | Yards | ave | TDs |
| Robinson, James | 12 | 29 | 2.4 | 1 |
| Lawrence, Trevor | 3 | 23 | 7.7 | 0 |
| Agnew, Jamal | 1 | 2 | 2.0 | 0 |
|
| Player | T/Rec | Yards | ave | TDs |
| Aiyuk, Brandon | 7/7 | 85 | 12.1 | 1 |
| Kittle, George | 4/4 | 34 | 8.5 | 1 |
| Sermon, Trey | 1/1 | 23 | 23.0 | 0 |
| Samuel, Deebo | 2/1 | 15 | 15.0 | 0 |
| Wilson Jr., Jeff | 2/1 | 8 | 8.0 | 0 |
| Juszczyk, Kyle | 2/1 | 7 | 7.0 | 0 |
| Jennings, Jauan | 1/1 | 4 | 4.0 | 0 |
|
| Player | T/Rec | Yards | ave | TDs |
| Jones Jr., Marvin | 6/4 | 52 | 13.0 | 0 |
| Shenault Jr., Laviska | 5/5 | 50 | 10.0 | 0 |
| Agnew, Jamal | 3/3 | 18 | 6.0 | 0 |
| Austin, Tavon | 2/1 | 18 | 18.0 | 0 |
| Treadwell, Laquon | 3/1 | 11 | 11.0 | 0 |
| Robinson, James | 3/2 | 9 | 4.5 | 0 |
|
| Player | XP/XA | FG/FGa | 1-39 | 40-49 | 50+ | FSV |
| Gould, Robbie | 3/3 | 3/3 | 1/1 | 2/2 | 0/0 | 12 |
|
| Player | XP/XA | FG/FGa | 1-39 | 40-49 | 50+ | FSV |
| Wright, Matthew | 1/1 | 1/1 | 1/1 | 0/0 | 0/0 | 4 |
|
| Player | Fum | F lost | F Rec | F Forc | F TDs |
| Warner, Fred | 0 | 0 | 1 | 0 | 0 |
| Norman, Josh | 0 | 0 | 0 | 1 | 0 |
|
| Player | Fum | F lost | F Rec | F Forc | F TDs |
| Allen, Josh | 0 | 0 | 0 | 1 | 0 |
|
| Player | Int | Ret. Yds. | Ret. TDs |
No Interceptions |
|
| Player | Int | Ret. Yds. | Ret. TDs |
No Interceptions |
|
| Player | Tackles | Assists | Sacks |
| Warner, Fred | 4 | 3 | 0 |
| Thomas, Ambry | 4 | 0 | 0 |
| Bosa, Nick | 3 | 0 | 2 |
| Ward, Jimmie | 2 | 3 | 0 |
| Williams, K'Waun | 2 | 2 | 0 |
| Hufanga, Talanoa | 2 | 1 | 0 |
| Moseley, Emmanuel | 1 | 0 | 0 |
| Jones, D.J. | 1 | 0 | 0 |
| Key, Arden | 1 | 1 | 1 |
| Givens, Kevin | 1 | 0 | 0 |
| Harris, Marcell | 1 | 1 | 0 |
| Street, Kentavius | 1 | 1 | 0 |
| Ebukam, Samson | 1 | 0 | 0 |
| Tartt, Jaquiski | 1 | 1 | 0 |
| Al_Shaair, Azeez | 1 | 1 | 0 |
| Armstead, Arik | 0 | 2 | 0 |
| Norman, Josh | 0 | 1 | 0 |
|
| Player | Tackles | Assists | Sacks |
| Jack, Myles | 5 | 7 | 0 |
| Allen, Josh | 4 | 6 | 0 |
| Wingard, Andrew | 4 | 3 | 0 |
| Wilson, Damien | 4 | 4 | 1 |
| Campbell, Tyson | 3 | 0 | 0 |
| Cisco, Andre | 3 | 0 | 0 |
| Lawson, Nevin | 3 | 0 | 0 |
| Chaisson, K'Lavon | 3 | 1 | 0 |
| Jenkins, Rayshawn | 2 | 0 | 0 |
| Robertson_Harris, Roy | 2 | 2 | 1 |
| Ford, Rudy | 2 | 2 | 0 |
| Thomas, Daniel | 2 | 2 | 0 |
| Brown, Malcom | 1 | 2 | 0 |
| McCray, Lerentee | 1 | 0 | 0 |
| Hamilton, Davon | 0 | 2 | 0 |
| Griffin, Shaquill | 0 | 1 | 0 |
| Ward, Jihad | 0 | 1 | 0 |
| Russell, Chapelle | 0 | 1 | 0 |
|
|
